YC_DSC

The purpose of this project was to investigate the relation between Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) diagnosis of ADHD and Child Behavioral Checklist Attention Problems (CBCL-AP) scores. Twins were selected based on their maternal CBCL-AP scores at ages 7, 10 and 12. Twin pairs were selected if at least one of the twins scored high on AP (affected pairs), or if both twins scored low on AP (control pairs). In families that agreed to participate, the mother of the twins was interviewed by telephone with the Diagnostic Interview Schedule for Children (DISC-IV). Other surveys that were collected are the CBCL, SWAN and YSR. Mouth swabs were used to collect buccal cell samples, from which DNA was extracted.

Cohort
Subject age
  • 10.0 - 13.0 years
Time span From 2002-01-01 to 2005-01-01
Geographic location NL
Publisher
Creators
Dorret I. Boomsma
Vrije Universiteit Amsterdam
Contributors
Eske M. Derks
Vrije Universiteit Amsterdam
Funding information
NIMH RO1
MH58799-03
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