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measure Inflammation markers
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort Early pregnancy Mid pregnancy 5-6 years 9-10 yearsInflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created May 3, 2023 • Updated May 3, 2023 -
measure Body composition and bone mineral density (dual X energy absorptiometry (DXA)...
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort 6 months 5-6 years 9-10 years 13-14 years Covid questionnairesThis dataset has no description
Created May 3, 2023 • Updated May 3, 2023 -
measure Lipids
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort Early pregnancy 5-6 years 9-10 yearsLipids, for instance Cholesterol, Triglycerides, Low-Density Lipoprotein Cholesterol (LDL-C), High-Density Lipoprotein Cholesterol (HDL-C), Lipoproteins, and Apolipoproteins measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created May 3, 2023 • Updated May 3, 2023 -
measure Bone mineral density and geometry of the tibia (Peripheral Quantitative Compu...
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort 9-10 years 13-14 years Covid questionnairesMeasurements of bone mineral density by peripheral quantitative computed tomography (CT) or dual X energy absorptiometry (DXA) scan. Geometry of the tibia by CT scan and body composition by DXA scanCreated May 3, 2023 • Updated May 3, 2023 -
measure LC-MS lipidomics
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort Early pregnancy 9-10 yearsLiquid chromatography mass spectrometry (LC-MS) platform targeting lipid species.Created May 3, 2023 • Updated May 3, 2023 -
measure Diffusion Tensor Imaging (DTI)
Study: Generation R Mode of collection: MeasurementsAndTests MRI Available measurements: Main Cohort 7 years 9-10 years 13-14 years Covid questionnairesDiffusion Tensor Imaging (DTI) is a Magnetic Resonance Imaging‑based neuroimaging technique that makes it possible to estimate the location, orientation, and anisotropy of the white matter tracts of the brain.Created May 3, 2023 • Updated May 3, 2023 -
measure Cardiac and renal structure
Study: Generation R Mode of collection: MeasurementsAndTests Echo Available measurements: Main Cohort 6 months 2 years 5-6 years 9-10 yearsThis dataset has no description
Created May 3, 2023 • Updated May 3, 2023 -
measure Saliva sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort 1.5 years 5-6 years 9-10 yearsHPA axis, Cortisol diurnal rhythm (@home) and stress reaction (@lab) @14 months, subgroupCreated May 3, 2023 • Updated May 3, 2023 -
measure Functional connectivity Magnetic Resonance Imaging (rs-fMRI)
Study: Generation R Mode of collection: MeasurementsAndTests MRI Available measurements: Main Cohort 7 years 9-10 years 13-14 years Covid questionnairesThis dataset has no description
Created May 3, 2023 • Updated May 3, 2023 -
measure LC-MS amines
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort Early pregnancy 9-10 yearsLiquid chromatography mass spectrometry (LC-MS) platform targeting amines.Created May 3, 2023 • Updated May 3, 2023 -
measure Structural Magnetic Resonance Imaging (MRI)
Study: Generation R Mode of collection: MeasurementsAndTests MRI Available measurements: Main Cohort 7 years 9-10 years 13-14 years Covid questionnairesStructural magnetic resonance imaging (MRI) is a non-invasive technique for examining the anatomy and pathology of the brain (as opposed to using functional magnetic resonance imaging [fMRI] to examine brain activity).Created May 3, 2023 • Updated May 3, 2023 -
measure Hair sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort 5-6 years 9-10 years 13-14 yearsA hair sample was obtained at age 6 to quantify several sex steroids, including cortisol, cortisone, 17OHP, androstenedione, testosterone and DHEAS. 3cm samples were taken from 100-200 hairs close to the scalp.Created May 3, 2023 • Updated May 3, 2023 -
measure GC-MS steroid hormones
Study: NTR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YC_BS1 YC_BS2 YC_BS3Gas chromatography mass spectrometry (GC-MS) platform targeting steroid hormones.Created March 28, 2023 • Updated April 4, 2023 -
measure GC-MS organic acids
Study: NTR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3Gas chromatography mass spectrometry (GC-MS) platform targeting organic acids.Created March 28, 2023 • Updated April 4, 2023 -
measure Saliva sample
Study: NTR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YC_BS1 YC_BS2 YC_BS3 YE_ATTEF2 YE_COG12 YE_COG18Saliva was collected using a cotton swab or a collection device, such as a tube or container (passive drool).Created March 28, 2023 • Updated April 4, 2023 -
measure Urine osmolality
Study: NTR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3Urinary osmolality as measured with density test (specific gravity) using the Atago refractometer PAL-10S BLT/A+W (Atago, Tokyo, Japan). The refractive index is a ratio of the velocity of light in air to the velocity of light in solution, which is directly proportional to the number of dissolved solids in urine.Created March 28, 2023 • Updated April 4, 2023 -
measure Peptide hormones
Study: NTR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_BS1 YC_BS2 YC_BS3Peptide hormones, for instance Adrenocorticotropic Hormone (ACTH, pituitary hormone), Alpha-Melanocyte-Stimulating Hormone (α-MSH, Melanocortin), Luteinizing Hormone (LH), Cholecytokinin, and Follicle Stimulating Hormone (FSH), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created March 28, 2023 • Updated April 4, 2023 -
measure Tanner Scale
Study: NTR Mode of collection: SelfAdministeredQuestionnaire Available measurements: Young Netherlands Twin Register YC_BS1 YC_BS2 YC_BS3 YE_ATTEF2 YE_COG12 YE_COG18The Tanner Scale describes, both pictorially and descriptively, the external changes that occur in the time period between the onset of puberty and the achievement of full maturity for both girls and boys. Characterizations of pubertal status are assessed by breast development in girls, genital development in boys and pubic hair growth in both. The Tanner...Created March 28, 2023 • Updated April 4, 2023 -
measure Liver enzymes
Study: NTR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3 YC_BS1 YC_BS2 YC_BS3Liver enzymes, for instance Albumin, Jodide, Aspartaat Aminotransferase (ASAT), and Alanine Transaminase (ALAT), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created March 28, 2023 • Updated April 4, 2023 -
measure Pubertal Development
Study: NTR Mode of collection: SelfAdministeredQuestionnaire Available measurements: Young Netherlands Twin Register YS_1 YS_DHBQP YS_DHBQ14 YS_DHBQ16 YS_DHBQ18 YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3 YC_BS1 YC_BS2 YC_BS3 YC_DSC YE_FITNSS YC_ADHMRI YE_COG18 YS_TRIP1_2Questions about pubertal development including breast growth, menstruation, shaving, deepening of voice, and growth spurtsCreated March 28, 2023 • Updated April 4, 2023