• measure Blood sugar markers

    Study:Generation R
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Main Cohort  Early pregnancy 5-6 years
    0
    30 years
    Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created May 3, 2023 • Updated May 3, 2023

  • measure Genotyping (array)

    Study:Generation R
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    0
    30 years
    Assessment of single nucleotide polymorphisms (SNPs) as obtained through genotyping arrays.
    Created May 3, 2023 • Updated May 3, 2023

  • measure Inflammation markers

    Study:Generation R
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Main Cohort  Early pregnancy Mid pregnancy 5-6 years 9-10 years
    0
    30 years
    Inflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created May 3, 2023 • Updated May 3, 2023

  • measure Lipids

    Study:Generation R
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Main Cohort  Early pregnancy 5-6 years 9-10 years
    0
    30 years
    Lipids, for instance Cholesterol, Triglycerides, Low-Density Lipoprotein Cholesterol (LDL-C), High-Density Lipoprotein Cholesterol (HDL-C), Lipoproteins, and Apolipoproteins measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created May 3, 2023 • Updated May 3, 2023

  • measure LC-MS lipidomics

    Study:Generation R
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Main Cohort  Early pregnancy 9-10 years
    0
    30 years
    Liquid chromatography mass spectrometry (LC-MS) platform targeting lipid species.
    Created May 3, 2023 • Updated May 3, 2023

  • measure Genotyping (array)

    Study:Generation R
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Main Cohort  Early pregnancy
    0
    30 years
    Assessment of single nucleotide polymorphisms (SNPs) as obtained through genotyping arrays.
    Created May 3, 2023 • Updated May 3, 2023

  • measure Saliva sample

    Study:Generation R
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Main Cohort  1.5 years 5-6 years 9-10 years
    0
    30 years
    HPA axis, Cortisol diurnal rhythm (@home) and stress reaction (@lab) @14 months, subgroup
    Created May 3, 2023 • Updated May 3, 2023

  • measure LC-MS amines

    Study:Generation R
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Main Cohort  Early pregnancy 9-10 years
    0
    30 years
    Liquid chromatography mass spectrometry (LC-MS) platform targeting amines.
    Created May 3, 2023 • Updated May 3, 2023

  • measure DNA methylation (array)

    Study:Generation R
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    0
    30 years
    Assessment of DNA methylation as obtained through DNA methylation arrays.
    Created May 3, 2023 • Updated May 3, 2023

  • measure Hair sample

    Study:Generation R
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Main Cohort  5-6 years 9-10 years 13-14 years
    0
    30 years
    A hair sample was obtained at age 6 to quantify several sex steroids, including cortisol, cortisone, 17OHP, androstenedione, testosterone and DHEAS. 3cm samples were taken from 100-200 hairs close to the scalp.
    Created May 3, 2023 • Updated May 3, 2023

  • measure GC-MS steroid hormones

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_BS1 YC_BS2 YC_BS3
    0
    30 years
    Gas chromatography mass spectrometry (GC-MS) platform targeting steroid hormones.
    Created March 28, 2023 • Updated April 4, 2023

  • measure GC-MS organic acids

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3
    0
    30 years
    Gas chromatography mass spectrometry (GC-MS) platform targeting organic acids.
    Created March 28, 2023 • Updated April 4, 2023

  • measure Saliva sample

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_BS1 YC_BS2 YC_BS3 YE_ATTEF2 YE_COG12 YE_COG18
    0
    30 years
    Saliva was collected using a cotton swab or a collection device, such as a tube or container (passive drool).
    Created March 28, 2023 • Updated April 4, 2023

  • measure Urine osmolality

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3
    0
    30 years
    Urinary osmolality as measured with density test (specific gravity) using the Atago refractometer PAL-10S BLT/A+W (Atago, Tokyo, Japan). The refractive index is a ratio of the velocity of light in air to the velocity of light in solution, which is directly proportional to the number of dissolved solids in urine.
    Created March 28, 2023 • Updated April 4, 2023

  • measure NMR metabolomics

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YE_COG18
    0
    30 years
    Untargeted proton nuclear magnetic resonance (1H-NMR) metabolomics platform.
    Created March 28, 2023 • Updated April 4, 2023

  • measure Peptide hormones

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_BS1 YC_BS2 YC_BS3
    0
    30 years
    Peptide hormones, for instance Adrenocorticotropic Hormone (ACTH, pituitary hormone), Alpha-Melanocyte-Stimulating Hormone (α-MSH, Melanocortin), Luteinizing Hormone (LH), Cholecytokinin, and Follicle Stimulating Hormone (FSH), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created March 28, 2023 • Updated April 4, 2023

  • measure Steroid hormones

    Study:RADAR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Cohort  W3 W4 W5
    0
    30 years
    Steroid hormones, for instance Testosterone, Estrogen, Dehydroepiandrosterone (DHEA), and Cortisol, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created March 28, 2023 • Updated April 4, 2023

  • measure Saliva sample

    Study:RADAR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Cohort  W5 W10
    0
    30 years
    Saliva was collected using a cotton swab or a collection device, such as a tube or container (passive drool).
    Created March 28, 2023 • Updated April 4, 2023

  • measure Liver enzymes

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3 YC_BS1 YC_BS2 YC_BS3
    0
    30 years
    Liver enzymes, for instance Albumin, Jodide, Aspartaat Aminotransferase (ASAT), and Alanine Transaminase (ALAT), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created March 28, 2023 • Updated April 4, 2023

  • measure Steroid hormones

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_BS1 YC_BS2 YC_BS3 YE_ATTEF2 YE_COG12 YE_COG18
    0
    30 years
    Steroid hormones, for instance Testosterone, Estrogen, Dehydroepiandrosterone (DHEA), and Cortisol, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created March 28, 2023 • Updated April 4, 2023
You can also access this registry using the API (see API Docs).