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measure Blood sugar markers
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort Early pregnancy 5-6 yearsBlood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created May 3, 2023 • Updated May 3, 2023 -
measure Genotyping (array)
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Assessment of single nucleotide polymorphisms (SNPs) as obtained through genotyping arrays.Created May 3, 2023 • Updated May 3, 2023 -
measure Inflammation markers
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort Early pregnancy Mid pregnancy 5-6 years 9-10 yearsInflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created May 3, 2023 • Updated May 3, 2023 -
measure Body composition and bone mineral density (dual X energy absorptiometry (DXA)...
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort 6 months 5-6 years 9-10 years 13-14 years Covid questionnairesThis dataset has no description
Created May 3, 2023 • Updated May 3, 2023 -
measure Lipids
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort Early pregnancy 5-6 years 9-10 yearsLipids, for instance Cholesterol, Triglycerides, Low-Density Lipoprotein Cholesterol (LDL-C), High-Density Lipoprotein Cholesterol (HDL-C), Lipoproteins, and Apolipoproteins measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created May 3, 2023 • Updated May 3, 2023 -
measure Bone mineral density and geometry of the tibia (Peripheral Quantitative Compu...
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort 9-10 years 13-14 years Covid questionnairesMeasurements of bone mineral density by peripheral quantitative computed tomography (CT) or dual X energy absorptiometry (DXA) scan. Geometry of the tibia by CT scan and body composition by DXA scanCreated May 3, 2023 • Updated May 3, 2023 -
measure Actigraphy
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort 11 years 13-14 yearsThis dataset has no description
Created May 3, 2023 • Updated May 3, 2023 -
measure LC-MS lipidomics
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort Early pregnancy 9-10 yearsLiquid chromatography mass spectrometry (LC-MS) platform targeting lipid species.Created May 3, 2023 • Updated May 3, 2023 -
measure Genotyping (array)
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort Early pregnancyAssessment of single nucleotide polymorphisms (SNPs) as obtained through genotyping arrays.Created May 3, 2023 • Updated May 3, 2023 -
measure Saliva sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort 1.5 years 5-6 years 9-10 yearsHPA axis, Cortisol diurnal rhythm (@home) and stress reaction (@lab) @14 months, subgroupCreated May 3, 2023 • Updated May 3, 2023 -
measure Arterial stiffness
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort 5-6 yearsThe distance between the recording sites at the carotid (proximal) and femoral (distal) artery was measured over the surface of the body to the nearest centimeter. Through piezoelectric sensors placed on the skin, the device collected signals to assess the time delay between the upstroke of carotid and femoral waveforms. Carotid-femoral pulse wave...Created May 3, 2023 • Updated May 3, 2023 -
measure LC-MS amines
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort Early pregnancy 9-10 yearsLiquid chromatography mass spectrometry (LC-MS) platform targeting amines.Created May 3, 2023 • Updated May 3, 2023 -
measure DNA methylation (candidate genes)
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: DNA methylation of selected candidate genes, such as Nuclear Receptor Subfamily 3 Group C Member 1 (NR3C1), Solute Carrier Family 6 Member 4 (SLC6A4), and Catechol-O-Methyltransferase (COMT).Created May 3, 2023 • Updated May 3, 2023 -
measure DNA methylation (array)
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Assessment of DNA methylation as obtained through DNA methylation arrays.Created May 3, 2023 • Updated May 3, 2023 -
measure Hair sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort 5-6 years 9-10 years 13-14 yearsA hair sample was obtained at age 6 to quantify several sex steroids, including cortisol, cortisone, 17OHP, androstenedione, testosterone and DHEAS. 3cm samples were taken from 100-200 hairs close to the scalp.Created May 3, 2023 • Updated May 3, 2023 -
measure GC-MS steroid hormones
Study: NTR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YC_BS1 YC_BS2 YC_BS3Gas chromatography mass spectrometry (GC-MS) platform targeting steroid hormones.Created March 28, 2023 • Updated April 4, 2023 -
measure GC-MS organic acids
Study: NTR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3Gas chromatography mass spectrometry (GC-MS) platform targeting organic acids.Created March 28, 2023 • Updated April 4, 2023 -
measure Saliva sample
Study: NTR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YC_BS1 YC_BS2 YC_BS3 YE_ATTEF2 YE_COG12 YE_COG18Saliva was collected using a cotton swab or a collection device, such as a tube or container (passive drool).Created March 28, 2023 • Updated April 4, 2023 -
measure Urine osmolality
Study: NTR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3Urinary osmolality as measured with density test (specific gravity) using the Atago refractometer PAL-10S BLT/A+W (Atago, Tokyo, Japan). The refractive index is a ratio of the velocity of light in air to the velocity of light in solution, which is directly proportional to the number of dissolved solids in urine.Created March 28, 2023 • Updated April 4, 2023 -
measure NMR metabolomics
Study: NTR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YE_COG18Untargeted proton nuclear magnetic resonance (1H-NMR) metabolomics platform.Created March 28, 2023 • Updated April 4, 2023