Dataset

YC_BS3

The main aim of this project was to explore to what extent genetic and environmental factors explain individual differences in brain development and cognition. The study was a part of a Dutch longitudinal study in which twins, their siblings and their parents were assessed at three years interval. This project included the measurement eight years after baseline, around the 17th birthday of the twins. Data collection included psychometric IQ tests, a comprehensive neuropsychological testing protocol, and parental and self-ratings of behavioral and emotional problems. Physical maturation was measured through assessment of Tanner stages. Hormonal levels were assessed in urine and saliva. Brain scans were acquired using 1.5 Tesla Magnetic Resonance Imaging (MRI), which provided volumetric measures and measures of cortical thickness. Buccal swabs were collected for DNA isolation for future genetic association studies.

Cohort	NTR: Young Netherlands Twin Register
Subject age	17.0 years
Time span	From 2012-01-01 to 2014-01-01
Geographic location	NL
Publisher	Vrije Universiteit Amsterdam
Creators	Dorret I. Boomsma Vrije Universiteit Amsterdam
Contributors	Suzanne Swagerman Vrije Universiteit Amsterdam Marinka Koenis Universiteit Utrecht
Funding information	NWO 433-09-220

You can also access this dataset using the API (see API Docs).

author	None
author_email	None
creator_user_id	6c404c5c-dbec-4933-bc54-0b7656c773ba
id	81b18ca3-d09d-430c-86c9-f5dda63ed71a
isopen	False
license_title	None
maintainer	None
maintainer_email	None
metadata_created	2023-03-28T10:01:20.790695
metadata_modified	2023-03-28T10:01:20.790704
name	687788658d4a22ff44185f6f5fce3259
notes	The main aim of this project was to explore to what extent genetic and environmental factors explain individual differences in brain development and cognition. The study was a part of a Dutch longitudinal study in which twins, their siblings and their parents were assessed at three years interval. This project included the measurement eight years after baseline, around the 17th birthday of the twins. Data collection included psychometric IQ tests, a comprehensive neuropsychological testing protocol, and parental and self-ratings of behavioral and emotional problems. Physical maturation was measured through assessment of Tanner stages. Hormonal levels were assessed in urine and saliva. Brain scans were acquired using 1.5 Tesla Magnetic Resonance Imaging (MRI), which provided volumetric measures and measures of cortical thickness. Buccal swabs were collected for DNA isolation for future genetic association studies.
num_resources	0
num_tags	0
organization	{'id': '1c79e3cf-de04-4f4c-aa77-46aff3228db4', 'name': 'ntr', 'title': 'NTR', 'type': 'organization', 'description': 'The Netherlands Twin Register (NTR) consists of individuals who have agreed to participate in twin-family studies and was established and is managed by the Department of Biological Psychology, VU University Amsterdam (see: https://tweelingenregister.vu.nl/). The NTR was established in 1987 and has enrolled around 120.000 twins and a roughly equal number of their relatives. The majority of twin families have participated one or more times in survey studies on a host of epidemiological variables including social demography, personality, lifestyle, somatic and mental health, and subsamples took part in biomaterial collection (e.g. DNA) and dedicated projects for e.g. neuropsychological, biomarker, and behavioural traits. The recruitment into the NTR is fully inclusive without any restrictions on enrolment. The NTR is committed to actively seek the commitment of its participants to science and their continued involvement in NTR research by maintaining a website, electronic newsletters, and the MijnNTR portal that provides personalized feedback to participants. The NTR resources, e.g. the longitudinal phenotyping, the extended pedigree structures, and the multi-generation genotyping allow for future twin-family research that will contribute to gene discovery, causality modelling, and studies of genetic and cultural inheritance of behavioural traits and mental and physical health. In the CD2 portal, only the NTR projects for children and adolescents (<18 years of age) have been included. This is refered to as the Young Netherlands Twin Register (YNTR).', 'image_url': 'https://beta.data.individualdevelopment.nl/img/logo_ntr.png', 'created': '2023-03-06T15:49:42.299075', 'is_organization': True, 'approval_status': 'approved', 'state': 'active'}
owner_org	1c79e3cf-de04-4f4c-aa77-46aff3228db4
private	False
state	active
title	YC_BS3
type	wave
wave_alternate_title	{"Brain Scale measurement 3","Brain Scale measurement t2","BrainScale age 17"}
wave_cohort	NTR: Young Netherlands Twin Register
wave_cohort_ckan_id	6f88a94b0bf79a8304ba604c655c08a9
wave_end_date_collection	2014-01-01
wave_spatial_country_code	NL
wave_spatial_highest_reference	country
wave_spatial_lowest_reference	postal code
wave_start_date_collection	2012-01-01
wave_universe	204
wave_contributors	[{'wave_contributor': 'Suzanne Swagerman', 'wave_contributor_affiliation': 'Vrije Universiteit Amsterdam', 'wave_contributor_identifier_type': '', 'wave_contributor_pid': ''}, {'wave_contributor': 'Marinka Koenis', 'wave_contributor_affiliation': 'Universiteit Utrecht', 'wave_contributor_identifier_type': 'ORCID', 'wave_contributor_pid': '0000-0002-3859-3847'}]
wave_creators	[{'wave_creator': 'Dorret I. Boomsma', 'wave_creator_affiliation': 'Vrije Universiteit Amsterdam', 'wave_creator_pid': '0000-0002-7099-7972'}]
wave_funding	[{'wave_funder': 'NWO', 'wave_grant_number': '433-09-220'}]
wave_publisher	[{'wave_publisher_identifier': 'https://ror.org/008xxew50', 'wave_publisher_identifier_type': 'ROR', 'wave_publisher_name': 'Vrije Universiteit Amsterdam'}]
resources	[]
tags	[]
groups	[]
relationships_as_subject	[]
relationships_as_object	[]
tracking_summary	{'total': 34, 'recent': 3}