• measure Body composition and bone mineral density (dual X energy absorptiometry (DXA)...

    Study:Generation R
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Main Cohort  6 months 5-6 years 9-10 years 13-14 years Covid questionnaires
    0
    30 years

    This dataset has no description

    Created May 3, 2023 • Updated May 3, 2023

  • measure Bone mineral density and geometry of the tibia (Peripheral Quantitative Compu...

    Study:Generation R
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Main Cohort  9-10 years 13-14 years Covid questionnaires
    0
    30 years
    Measurements of bone mineral density by peripheral quantitative computed tomography (CT) or dual X energy absorptiometry (DXA) scan. Geometry of the tibia by CT scan and body composition by DXA scan
    Created May 3, 2023 • Updated May 3, 2023

  • measure Actigraphy

    Study:Generation R
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Main Cohort  11 years 13-14 years
    0
    30 years

    This dataset has no description

    Created May 3, 2023 • Updated May 3, 2023

  • measure Diffusion Tensor Imaging (DTI)

    Study:Generation R
    Mode of collection:MeasurementsAndTests   MRI
    Available measurements:
    Main Cohort  7 years 9-10 years 13-14 years Covid questionnaires
    0
    30 years
    Diffusion Tensor Imaging (DTI) is a Magnetic Resonance Imaging‑based neuroimaging technique that makes it possible to estimate the location, orientation, and anisotropy of the white matter tracts of the brain.
    Created May 3, 2023 • Updated May 3, 2023

  • measure Functional connectivity Magnetic Resonance Imaging (rs-fMRI)

    Study:Generation R
    Mode of collection:MeasurementsAndTests   MRI
    Available measurements:
    Main Cohort  7 years 9-10 years 13-14 years Covid questionnaires
    0
    30 years

    This dataset has no description

    Created May 3, 2023 • Updated May 3, 2023

  • measure Structural Magnetic Resonance Imaging (MRI)

    Study:Generation R
    Mode of collection:MeasurementsAndTests   MRI
    Available measurements:
    Main Cohort  7 years 9-10 years 13-14 years Covid questionnaires
    0
    30 years
    Structural magnetic resonance imaging (MRI) is a non-invasive technique for examining the anatomy and pathology of the brain (as opposed to using functional magnetic resonance imaging [fMRI] to examine brain activity).
    Created May 3, 2023 • Updated May 3, 2023

  • measure Hair sample

    Study:Generation R
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Main Cohort  5-6 years 9-10 years 13-14 years
    0
    30 years
    A hair sample was obtained at age 6 to quantify several sex steroids, including cortisol, cortisone, 17OHP, androstenedione, testosterone and DHEAS. 3cm samples were taken from 100-200 hairs close to the scalp.
    Created May 3, 2023 • Updated May 3, 2023

  • measure GC-MS organic acids

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3
    0
    30 years
    Gas chromatography mass spectrometry (GC-MS) platform targeting organic acids.
    Created March 28, 2023 • Updated April 4, 2023

  • measure Urine osmolality

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3
    0
    30 years
    Urinary osmolality as measured with density test (specific gravity) using the Atago refractometer PAL-10S BLT/A+W (Atago, Tokyo, Japan). The refractive index is a ratio of the velocity of light in air to the velocity of light in solution, which is directly proportional to the number of dissolved solids in urine.
    Created March 28, 2023 • Updated April 4, 2023

  • measure Peptide hormones

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_BS1 YC_BS2 YC_BS3
    0
    30 years
    Peptide hormones, for instance Adrenocorticotropic Hormone (ACTH, pituitary hormone), Alpha-Melanocyte-Stimulating Hormone (α-MSH, Melanocortin), Luteinizing Hormone (LH), Cholecytokinin, and Follicle Stimulating Hormone (FSH), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created March 28, 2023 • Updated April 4, 2023

  • measure Liver enzymes

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3 YC_BS1 YC_BS2 YC_BS3
    0
    30 years
    Liver enzymes, for instance Albumin, Jodide, Aspartaat Aminotransferase (ASAT), and Alanine Transaminase (ALAT), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created March 28, 2023 • Updated April 4, 2023

  • measure Pubertal Development

    Study:NTR
    Mode of collection:SelfAdministeredQuestionnaire
    Available measurements:
    Young Netherlands Twin Register  YS_1 YS_DHBQP YS_DHBQ14 YS_DHBQ16 YS_DHBQ18 YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3 YC_BS1 YC_BS2 YC_BS3 YC_DSC YE_FITNSS YC_ADHMRI YE_COG18 YS_TRIP1_2
    0
    30 years
    Questions about pubertal development including breast growth, menstruation, shaving, deepening of voice, and growth spurts
    Created March 28, 2023 • Updated April 4, 2023

  • measure Oxidative stress markers

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3
    0
    30 years
    Oxidative stress markers, including Oxidized DNA/RNA, Total Antioxidant Capacity, and Thiobarbituric acid reactive substances (malondialdehyde), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created March 28, 2023 • Updated April 4, 2023

  • measure Inflammation markers

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3
    0
    30 years
    Inflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created March 28, 2023 • Updated April 4, 2023

  • measure Viral infections

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2
    0
    30 years
    Viral and parasitic infection loads, for instance Influenza A, Influenza B, Herpes Simplex Virus 1 (HSV1), Herpes Simplex Virus 2 (HSV2), Toxoplasma Gondii, Cytomegalovirus (CMV), Epstein-Barr Virus (EBV), and Procalcitonin, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created March 28, 2023 • Updated April 4, 2023

  • measure DNA methylation (array)

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTIONBB3
    0
    30 years
    Assessment of DNA methylation as obtained through DNA methylation arrays.
    Created March 28, 2023 • Updated April 4, 2023

  • measure Zygosity (DNA)

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YS_3 YS_5 YS_7 YS_10 YS_12 YS_DHBQ14 YS_DHBQ16 YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3 YC_BS1 YC_BS2 YC_BS3 YC_DSC YE_FITNSS YE_ATTEF1 YE_ATTEF2 YE_ATTEF3 YC_ADHMRI YE_COG18 YS_TRIP1_2 YS_TRIP3 YS_TRIP4 YS_TRIP5 YS_TRIP7 YS_TRIP10 YS_TRIP12
    0
    30 years
    Zygosity typing based on micro-satellite markers, single nucleotide polymorphisms (SNP), or variable number (short) tandem repeats (VNTRs).
    Created March 28, 2023 • Updated April 4, 2023

  • measure LC-MS amines

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3
    0
    30 years
    Liquid chromatography mass spectrometry (LC-MS) platform targeting amines.
    Created March 28, 2023 • Updated April 4, 2023

  • measure LC-MS steroid hormones

    Study:NTR
    Mode of collection:MeasurementsAndTests   Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTIONBB2 YC_ACTIONBB3 YC_BS1
    0
    30 years
    Liquid chromatography mass spectrometry (LC-MS) platform targeting steroid hormones.
    Created March 28, 2023 • Updated April 4, 2023

  • measure Anthropometry

    Study:NTR
    Mode of collection:SelfAdministeredQuestionnaire
    Available measurements:
    Young Netherlands Twin Register  YS_1 YS_2 YS_3 YS_5 YS_7 YS_10 YS_12 YS_DHBQP YS_DHBQ14 YS_DHBQ16 YS_DHBQ18 YC_BS1 YC_BS2 YC_BS3 YC_DSC YE_FITNSS YE_ATTEF2 YE_ATTEF3 YC_ADHMRI YE_COG18 YS_TRIP1 YS_TRIP2 YS_TRIP1_2 YS_TRIP3 YS_TRIP4 YS_TRIP5 YS_TRIP7 YS_TRIP10 YS_TRIP12
    0
    30 years
    Anthropometric measurements incl. height, weight, body mass index (BMI), and body circumferences
    Created March 28, 2023 • Updated April 4, 2023
You can also access this registry using the API (see API Docs).