Oxidative stress markers

Oxidative stress markers, including Oxidized DNA/RNA, Total Antioxidant Capacity, and Thiobarbituric acid reactive substances (malondialdehyde), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).

Total Antioxidant Capacity (YC_ACTIONBB1_1, YC_ACTIONBB1_2, YC_ACTIONBB2), thiobarbituric acid reactive substances (i.e., malondialdehyde) (YC_ACTIONBB1_1, YC_ACTIONBB1_2, YC_ACTIONBB2), and Oxidized DNA/RNA (i.e., oxidized guanine species: 8-hydroxyguanosine, 8-hydroxy-2’-deoxyguanosine, and 8-hydroxyguanine) (YC_ACTIONBB1_1, YC_ACTIONBB1_2, YC_ACTIONBB2, YC_ACTIONBB3) were measured in urine with ELISA. For more information see: Appendix 2 dissertation Fiona Hagenbeek (https://research.vu.nl/en/publications/omics-biomarkers-and-aggressive-behavior)

Labels
Constructs
Available measurements
  • Young Netherlands Twin Register

  • YC_ACTIONBB1_1
    • C
    10.0 - 13.0 years   From 2014-01-01 to 2015-01-01
  • YC_ACTIONBB1_2
    • C
    10.0 - 13.0 years   From 2014-01-01 to 2015-01-01
  • YC_ACTIONBB2
    • C
    6.0 - 11.0 years   From 2015-01-01 to 2015-01-01
  • YC_ACTIONBB3
    • C
    6.0 - 13.0 years   From 2016-01-01 to 2017-01-01
    Mode of collection MeasurementsAndTests   Biological sample/measurement
    References
    Hagenbeek, F. A., Roetman, P. J., Pool, R., Kluft, C., Harms, A. C., van Dongen, J., Colins, O. F., Talens, S., van Beijsterveldt, C. E. M., Vandenbosch, M. M. L. J. Z., de Zeeuw, E. L., Déjean, S., Fanos, V., Ehli, E. A., Davies, G. E., Hottenga, J. J., Hankemeier, T., Bartels, M., Vermeiren, R. R. J. M., & Boomsma, D. I. (2020). Urinary Amine and Organic Acid Metabolites Evaluated as Markers for Childhood Aggression: The ACTION Biomarker Study. Frontiers in Psychiatry, 11. https://doi.org/10.3389/fpsyt.2020.00165
    You can also access this dataset using the API (see API Docs).