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measure Inflammation markers
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort Early pregnancy Mid pregnancy 5-6 years 9-10 yearsInflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created May 3, 2023 • Updated May 3, 2023 -
measure Body composition and bone mineral density (dual X energy absorptiometry (DXA)...
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort 6 months 5-6 years 9-10 years 13-14 years Covid questionnairesThis dataset has no description
Created May 3, 2023 • Updated May 3, 2023 -
measure Lipids
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort Early pregnancy 5-6 years 9-10 yearsLipids, for instance Cholesterol, Triglycerides, Low-Density Lipoprotein Cholesterol (LDL-C), High-Density Lipoprotein Cholesterol (HDL-C), Lipoproteins, and Apolipoproteins measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created May 3, 2023 • Updated May 3, 2023 -
measure Bone mineral density and geometry of the tibia (Peripheral Quantitative Compu...
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort 9-10 years 13-14 years Covid questionnairesMeasurements of bone mineral density by peripheral quantitative computed tomography (CT) or dual X energy absorptiometry (DXA) scan. Geometry of the tibia by CT scan and body composition by DXA scanCreated May 3, 2023 • Updated May 3, 2023 -
measure LC-MS lipidomics
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort Early pregnancy 9-10 yearsLiquid chromatography mass spectrometry (LC-MS) platform targeting lipid species.Created May 3, 2023 • Updated May 3, 2023 -
measure Diffusion Tensor Imaging (DTI)
Study: Generation R Mode of collection: MeasurementsAndTests MRI Available measurements: Main Cohort 7 years 9-10 years 13-14 years Covid questionnairesDiffusion Tensor Imaging (DTI) is a Magnetic Resonance Imaging‑based neuroimaging technique that makes it possible to estimate the location, orientation, and anisotropy of the white matter tracts of the brain.Created May 3, 2023 • Updated May 3, 2023 -
measure Cardiac and renal structure
Study: Generation R Mode of collection: MeasurementsAndTests Echo Available measurements: Main Cohort 6 months 2 years 5-6 years 9-10 yearsThis dataset has no description
Created May 3, 2023 • Updated May 3, 2023 -
measure Saliva sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort 1.5 years 5-6 years 9-10 yearsHPA axis, Cortisol diurnal rhythm (@home) and stress reaction (@lab) @14 months, subgroupCreated May 3, 2023 • Updated May 3, 2023 -
measure Functional connectivity Magnetic Resonance Imaging (rs-fMRI)
Study: Generation R Mode of collection: MeasurementsAndTests MRI Available measurements: Main Cohort 7 years 9-10 years 13-14 years Covid questionnairesThis dataset has no description
Created May 3, 2023 • Updated May 3, 2023 -
measure LC-MS amines
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort Early pregnancy 9-10 yearsLiquid chromatography mass spectrometry (LC-MS) platform targeting amines.Created May 3, 2023 • Updated May 3, 2023 -
measure Structural Magnetic Resonance Imaging (MRI)
Study: Generation R Mode of collection: MeasurementsAndTests MRI Available measurements: Main Cohort 7 years 9-10 years 13-14 years Covid questionnairesStructural magnetic resonance imaging (MRI) is a non-invasive technique for examining the anatomy and pathology of the brain (as opposed to using functional magnetic resonance imaging [fMRI] to examine brain activity).Created May 3, 2023 • Updated May 3, 2023 -
measure Hair sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Main Cohort 5-6 years 9-10 years 13-14 yearsA hair sample was obtained at age 6 to quantify several sex steroids, including cortisol, cortisone, 17OHP, androstenedione, testosterone and DHEAS. 3cm samples were taken from 100-200 hairs close to the scalp.Created May 3, 2023 • Updated May 3, 2023 -
measure GC-MS organic acids
Study: NTR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3Gas chromatography mass spectrometry (GC-MS) platform targeting organic acids.Created March 28, 2023 • Updated April 4, 2023 -
measure Urine osmolality
Study: NTR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3Urinary osmolality as measured with density test (specific gravity) using the Atago refractometer PAL-10S BLT/A+W (Atago, Tokyo, Japan). The refractive index is a ratio of the velocity of light in air to the velocity of light in solution, which is directly proportional to the number of dissolved solids in urine.Created March 28, 2023 • Updated April 4, 2023 -
measure Liver enzymes
Study: NTR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3 YC_BS1 YC_BS2 YC_BS3Liver enzymes, for instance Albumin, Jodide, Aspartaat Aminotransferase (ASAT), and Alanine Transaminase (ALAT), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created March 28, 2023 • Updated April 4, 2023 -
measure Pubertal Development
Study: NTR Mode of collection: SelfAdministeredQuestionnaire Available measurements: Young Netherlands Twin Register YS_1 YS_DHBQP YS_DHBQ14 YS_DHBQ16 YS_DHBQ18 YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3 YC_BS1 YC_BS2 YC_BS3 YC_DSC YE_FITNSS YC_ADHMRI YE_COG18 YS_TRIP1_2Questions about pubertal development including breast growth, menstruation, shaving, deepening of voice, and growth spurtsCreated March 28, 2023 • Updated April 4, 2023 -
measure Oxidative stress markers
Study: NTR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3Oxidative stress markers, including Oxidized DNA/RNA, Total Antioxidant Capacity, and Thiobarbituric acid reactive substances (malondialdehyde), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created March 28, 2023 • Updated April 4, 2023 -
measure Inflammation markers
Study: NTR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2 YC_ACTIONBB3Inflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created March 28, 2023 • Updated April 4, 2023 -
measure Viral infections
Study: NTR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YC_ACTIONBB1_1 YC_ACTIONBB1_2 YC_ACTIONBB2Viral and parasitic infection loads, for instance Influenza A, Influenza B, Herpes Simplex Virus 1 (HSV1), Herpes Simplex Virus 2 (HSV2), Toxoplasma Gondii, Cytomegalovirus (CMV), Epstein-Barr Virus (EBV), and Procalcitonin, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created March 28, 2023 • Updated April 4, 2023 -
measure DNA methylation (array)
Study: NTR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YC_ACTIONBB3Assessment of DNA methylation as obtained through DNA methylation arrays.Created March 28, 2023 • Updated April 4, 2023