| author | None |
| author_email | None |
| creator_user_id | 6c404c5c-dbec-4933-bc54-0b7656c773ba |
| dc_additional_info | In YC_BS2 and YC_BS3 resting state fMRI was obtained from whole head MRI scan acquired with a 1.5 Tesla Philips Achieva scanner (Philips, Best, The Netherlands, for protocol details see: https://doi.org/10.1017/thg.2012.4). In YC_ADHMRI functional scanning was performed during the Stroop color-word task and a modified version of the Eriksen flanker task. During these tasks, the fMRI BOLD (blood oxygen level dependent) signal was recorded (see: https://doi.org/10.1016/j.neuroscience.2009.01.056). |
| dc_analysis_unit | [] |
| dc_cohort | NTR |
| dc_mode_of_collection | MeasurementsAndTests |
| dc_mode_of_collection_sub | MRI |
| id | e5db31ac-51b0-4b91-9bc3-13bacaa61a60 |
| isopen | False |
| license_title | None |
| maintainer | None |
| maintainer_email | None |
| metadata_created | 2023-03-28T10:01:10.813387 |
| metadata_modified | 2023-04-04T12:48:53.446953 |
| name | 908bf854d9a829a1345b0f46f402fbaa |
| notes | functional magnetic resonance imaging (MRI) is a non-invasive technique for examining brain activity. |
| num_resources | 0 |
| num_tags | 0 |
| organization | {'id': '1c79e3cf-de04-4f4c-aa77-46aff3228db4', 'name': 'ntr', 'title': 'NTR', 'type': 'organization', 'description': 'The Netherlands Twin Register (NTR) consists of individuals who have agreed to participate in twin-family studies and was established and is managed by the Department of Biological Psychology, VU University Amsterdam (see: https://tweelingenregister.vu.nl/). The NTR was established in 1987 and has enrolled around 120.000 twins and a roughly equal number of their relatives. The majority of twin families have participated one or more times in survey studies on a host of epidemiological variables including social demography, personality, lifestyle, somatic and mental health, and subsamples took part in biomaterial collection (e.g. DNA) and dedicated projects for e.g. neuropsychological, biomarker, and behavioural traits. The recruitment into the NTR is fully inclusive without any restrictions on enrolment. The NTR is committed to actively seek the commitment of its participants to science and their continued involvement in NTR research by maintaining a website, electronic newsletters, and the MijnNTR portal that provides personalized feedback to participants. The NTR resources, e.g. the longitudinal phenotyping, the extended pedigree structures, and the multi-generation genotyping allow for future twin-family research that will contribute to gene discovery, causality modelling, and studies of genetic and cultural inheritance of behavioural traits and mental and physical health. In the CD2 portal, only the NTR projects for children and adolescents (<18 years of age) have been included. This is refered to as the Young Netherlands Twin Register (YNTR).', 'image_url': 'https://beta.data.individualdevelopment.nl/img/logo_ntr.png', 'created': '2023-03-06T15:49:42.299075', 'is_organization': True, 'approval_status': 'approved', 'state': 'active'} |
| owner_org | 1c79e3cf-de04-4f4c-aa77-46aff3228db4 |
| private | False |
| state | active |
| title | fuctional Magnetic Resonance Imaging (fMRI) |
| type | dataset |
| dc_constructs | [{'dc_construct': 'physiology'}] |
| dc_labels | [{'dc_label': 'biology'}, {'dc_label': 'brain imaging'}, {'dc_label': 'cognition'}, {'dc_label': 'functional brain imaging'}] |
| measure_age_range | [{'measure_age_month': 144}, {'measure_age_month': 180}, {'measure_age_month': 204}] |
| wave | [{'wave_ckan_id': 'c5467bc75c9c3b0964e9d728cd3d56f0', 'wave_cohort': 'NTR: Young Netherlands Twin Register', 'wave_cohort_ckan_id': '6f88a94b0bf79a8304ba604c655c08a9', 'wave_description': 'The main aim of this project was to explore to what extent genetic and environmental factors explain individual differences in brain development and cognition. The study was a part of a Dutch longitudinal study in which twins, their siblings and their parents were assessed at three years interval. This project included the measurement three years after baseline, around the 12th birthday of the twins. Data collection included psychometric IQ tests, a comprehensive neuropsychological testing protocol, and parental and self-ratings of behavioral and emotional problems. Physical maturation was measured through assessment of Tanner stages. Hormonal levels (cortisol, luteinizing hormone, follicle-stimulating hormone, testosterone, and estrogens) were assessed in urine and saliva. Brain scans were acquired using 1.5 Tesla Magnetic Resonance Imaging (MRI), which provided volumetric measures and measures of cortical thickness. Buccal swabs were collected for DNA isolation for future candidate gene and genome-wide analysis studies.', 'wave_end_date_collection': '2009-01-01', 'wave_start_date_collection': '2007-01-01', 'wave_subject_codes': ['C', 'S'], 'wave_title': 'YC_BS2', 'wave_universe': '144'}, {'wave_ckan_id': '687788658d4a22ff44185f6f5fce3259', 'wave_cohort': 'NTR: Young Netherlands Twin Register', 'wave_cohort_ckan_id': '6f88a94b0bf79a8304ba604c655c08a9', 'wave_description': 'The main aim of this project was to explore to what extent genetic and environmental factors explain individual differences in brain development and cognition. The study was a part of a Dutch longitudinal study in which twins, their siblings and their parents were assessed at three years interval. This project included the measurement eight years after baseline, around the 17th birthday of the twins. Data collection included psychometric IQ tests, a comprehensive neuropsychological testing protocol, and parental and self-ratings of behavioral and emotional problems. Physical maturation was measured through assessment of Tanner stages. Hormonal levels were assessed in urine and saliva. Brain scans were acquired using 1.5 Tesla Magnetic Resonance Imaging (MRI), which provided volumetric measures and measures of cortical thickness. Buccal swabs were collected for DNA isolation for future genetic association studies.', 'wave_end_date_collection': '2014-01-01', 'wave_start_date_collection': '2012-01-01', 'wave_subject_codes': ['C', 'S'], 'wave_title': 'YC_BS3', 'wave_universe': '204'}, {'wave_ckan_id': 'da08497f2ef7d7868f6ef93b9ad8d22f', 'wave_cohort': 'NTR: Young Netherlands Twin Register', 'wave_cohort_ckan_id': '6f88a94b0bf79a8304ba604c655c08a9', 'wave_description': 'Within the ADHD-MRI project, the genetic and environmental influence on ADHD related neurobiological changes were investigated in monozygotic twins. Twins were selected based on their Child Behavior Checklist Attention Problems (CBCL-AP) scores obtained in the regular YNTR survey waves and divided into three groups: discordant pairs (one affected, one unaffected), concordant pairs (both affected) and control pairs (both unaffected). To determine the presence of ADHD, mothers of the participants were interviewed with the Diagnostic Interview Schedule for Children (DISC-IV). Additionally, they filled in two behavioral questionnaires (CBCL and Strengths and Weaknesses of ADHD Symptoms and Normal Behavior (SWAN)). The twins filled in the Youth Self Report (YSR). Based on the outcome of the interview and questionnaires, twin pairs that were found eligible for the MRI experiments were invited. Both structural and functional MRI (color-stroop and flanker tasks) were performed. DNA was collected to confirm zygosity.', 'wave_end_date_collection': '2007-01-01', 'wave_start_date_collection': '2003-01-01', 'wave_subject_codes': ['C'], 'wave_title': 'YC_ADHMRI', 'wave_universe': '180'}] |
| resources | [] |
| tags | [] |
| groups | [] |
| relationships_as_subject | [] |
| relationships_as_object | [] |
| tracking_summary | {'total': 33, 'recent': 4} |
