| author | None |
| author_email | None |
| creator_user_id | 6c404c5c-dbec-4933-bc54-0b7656c773ba |
| dc_analysis_unit | [] |
| dc_cohort | NTR |
| dc_mode_of_collection | SelfAdministeredQuestionnaire |
| id | 229c213b-9a96-40ef-b480-74b7cb5686d8 |
| isopen | False |
| license_title | None |
| maintainer | None |
| maintainer_email | None |
| metadata_created | 2023-03-28T10:01:28.176171 |
| metadata_modified | 2023-04-04T12:49:04.619263 |
| name | ba151dfa48ad80f45d7c691ca628f658 |
| notes | Questions about nutritional supplement use by mother during pregnancy and vitamin supplementation use of children, including formation regarding type, frequency, and duration of vitamin supplementation |
| num_resources | 0 |
| num_tags | 0 |
| organization | {'id': '1c79e3cf-de04-4f4c-aa77-46aff3228db4', 'name': 'ntr', 'title': 'NTR', 'type': 'organization', 'description': 'The Netherlands Twin Register (NTR) consists of individuals who have agreed to participate in twin-family studies and was established and is managed by the Department of Biological Psychology, VU University Amsterdam (see: https://tweelingenregister.vu.nl/). The NTR was established in 1987 and has enrolled around 120.000 twins and a roughly equal number of their relatives. The majority of twin families have participated one or more times in survey studies on a host of epidemiological variables including social demography, personality, lifestyle, somatic and mental health, and subsamples took part in biomaterial collection (e.g. DNA) and dedicated projects for e.g. neuropsychological, biomarker, and behavioural traits. The recruitment into the NTR is fully inclusive without any restrictions on enrolment. The NTR is committed to actively seek the commitment of its participants to science and their continued involvement in NTR research by maintaining a website, electronic newsletters, and the MijnNTR portal that provides personalized feedback to participants. The NTR resources, e.g. the longitudinal phenotyping, the extended pedigree structures, and the multi-generation genotyping allow for future twin-family research that will contribute to gene discovery, causality modelling, and studies of genetic and cultural inheritance of behavioural traits and mental and physical health. In the CD2 portal, only the NTR projects for children and adolescents (<18 years of age) have been included. This is refered to as the Young Netherlands Twin Register (YNTR).', 'image_url': 'https://beta.data.individualdevelopment.nl/img/logo_ntr.png', 'created': '2023-03-06T15:49:42.299075', 'is_organization': True, 'approval_status': 'approved', 'state': 'active'} |
| owner_org | 1c79e3cf-de04-4f4c-aa77-46aff3228db4 |
| private | False |
| state | active |
| title | Supplement use |
| type | dataset |
| dc_constructs | [{'dc_construct': 'life history'}] |
| dc_labels | [{'dc_label': 'medication'}, {'dc_label': 'metabolism'}, {'dc_label': 'nutrition'}, {'dc_label': 'pregnancy'}, {'dc_label': 'supplements'}] |
| measure_age_range | [{'measure_age_month': 0}, {'measure_age_month': 1}, {'measure_age_month': 2}, {'measure_age_month': 3}, {'measure_age_month': 4}, {'measure_age_month': 5}, {'measure_age_month': 6}, {'measure_age_month': 7}, {'measure_age_month': 8}, {'measure_age_month': 9}, {'measure_age_month': 10}, {'measure_age_month': 11}, {'measure_age_month': 12}, {'measure_age_month': 13}, {'measure_age_month': 14}, {'measure_age_month': 15}, {'measure_age_month': 16}, {'measure_age_month': 17}, {'measure_age_month': 18}, {'measure_age_month': 19}, {'measure_age_month': 20}, {'measure_age_month': 21}, {'measure_age_month': 22}, {'measure_age_month': 23}, {'measure_age_month': 24}, {'measure_age_month': 72}, {'measure_age_month': 73}, {'measure_age_month': 74}, {'measure_age_month': 75}, {'measure_age_month': 76}, {'measure_age_month': 77}, {'measure_age_month': 78}, {'measure_age_month': 79}, {'measure_age_month': 80}, {'measure_age_month': 81}, {'measure_age_month': 82}, {'measure_age_month': 83}, {'measure_age_month': 84}, {'measure_age_month': 85}, {'measure_age_month': 86}, {'measure_age_month': 87}, {'measure_age_month': 88}, {'measure_age_month': 89}, {'measure_age_month': 90}, {'measure_age_month': 91}, {'measure_age_month': 92}, {'measure_age_month': 93}, {'measure_age_month': 94}, {'measure_age_month': 95}, {'measure_age_month': 96}, {'measure_age_month': 97}, {'measure_age_month': 98}, {'measure_age_month': 99}, {'measure_age_month': 100}, {'measure_age_month': 101}, {'measure_age_month': 102}, {'measure_age_month': 103}, {'measure_age_month': 104}, {'measure_age_month': 105}, {'measure_age_month': 106}, {'measure_age_month': 107}, {'measure_age_month': 108}, {'measure_age_month': 109}, {'measure_age_month': 110}, {'measure_age_month': 111}, {'measure_age_month': 112}, {'measure_age_month': 113}, {'measure_age_month': 114}, {'measure_age_month': 115}, {'measure_age_month': 116}, {'measure_age_month': 117}, {'measure_age_month': 118}, {'measure_age_month': 119}, {'measure_age_month': 120}, {'measure_age_month': 121}, {'measure_age_month': 122}, {'measure_age_month': 123}, {'measure_age_month': 124}, {'measure_age_month': 125}, {'measure_age_month': 126}, {'measure_age_month': 127}, {'measure_age_month': 128}, {'measure_age_month': 129}, {'measure_age_month': 130}, {'measure_age_month': 131}, {'measure_age_month': 132}, {'measure_age_month': 133}, {'measure_age_month': 134}, {'measure_age_month': 135}, {'measure_age_month': 136}, {'measure_age_month': 137}, {'measure_age_month': 138}, {'measure_age_month': 139}, {'measure_age_month': 140}, {'measure_age_month': 141}, {'measure_age_month': 142}, {'measure_age_month': 143}, {'measure_age_month': 144}, {'measure_age_month': 145}, {'measure_age_month': 146}, {'measure_age_month': 147}, {'measure_age_month': 148}, {'measure_age_month': 149}, {'measure_age_month': 150}, {'measure_age_month': 151}, {'measure_age_month': 152}, {'measure_age_month': 153}, {'measure_age_month': 154}, {'measure_age_month': 155}, {'measure_age_month': 156}, {'measure_age_month': 216}] |
| wave | [{'wave_ckan_id': '3a693dad9a44a89bc4eb0573d6772dc1', 'wave_cohort': 'NTR: Young Netherlands Twin Register', 'wave_cohort_ckan_id': '6f88a94b0bf79a8304ba604c655c08a9', 'wave_description': 'After registration of newborn twins, which is before the age of 12 months for 89% of the twins, the mother of a twin pair receives the first survey which focuses on conception (spontaneous or otherwise), information from parents themselves (demographics, height, weight), pregnancy (e.g. duration, smoking and drinking behaviors of both parents during pregnancy), birth and health (malformations) of the children shortly after birth. The mother is asked to fill in this survey, and this was done by the biological mother for almost all of surveys with others (stepmother, adoptive mother, some fathers) completing this survey in a small number of families (<0.05%).', 'wave_start_date_collection': '1987-01-01', 'wave_subject_codes': ['MM'], 'wave_title': 'YS_1', 'wave_universe': '0-12'}, {'wave_ckan_id': '2698643e5b9a7a2b266f22734b0967aa', 'wave_cohort': 'NTR: Young Netherlands Twin Register', 'wave_cohort_ckan_id': '6f88a94b0bf79a8304ba604c655c08a9', 'wave_description': 'This is the Biochemical Study of the ACTION project (Aggression in Children: Unraveling gene-environment interplay to inform Treatment and interventION strategies Consortium; http://www.action-euproject.eu/). The aim of the biochemical study was to further validate the biomarker assays and metabolomics platforms selected during the technical pilot in a larger twin sample. The twins were selected based on their mother-rated aggression scores (Achenbach System of Empirically Based Assessment (ASEBA) Child Behavior Checklist) at age 3 and/or 7. The Biochemical study comprised concordant low-scoring twin pairs, concordant high-scoring twin pairs, and a discordant low-high scoring twin pairs. High aggression was defined as having an ASEBA CBCL Aggression Syndrome Scale T-score equal to or larger than 65, and low aggression as an ASEBA CBCL Aggression Syndrome Scale T-score of less than 65. Here, data collection comprised of first-morning urine samples and buccal-cell DNA samples in the twins and family members living at the same address as the participating twin pairs were also asked to provide a buccal-cell DNA sample. During the urine and buccal-cell collection, parents of the twins were asked to complete the ASEBA CBCL for school-aged children (6-18 years) to reflect the current child behaviors, and to provide information about health condition of the twins and conditions of urine collection. Biochemical measurement in urine included a dipstick, density (specific gravity), creatinine, neopterin, C-peptide, Substance P, oxidized DNA/RNA, procalcitonin, total antioxidant capacity, and glucose, and two metabolomics platforms: 1) a liquid chromatography mass spectrometry (LC-MS) platform targeting amines; and 2) a LC-MS platform targeting steroid hormones. Buccal-cell samples genotyped on the Affymetrix Axiom genotyping array. ', 'wave_end_date_collection': '2015-01-01', 'wave_start_date_collection': '2015-01-01', 'wave_subject_codes': ['PC'], 'wave_title': 'YC_ACTIONBB2', 'wave_universe': '72-132'}, {'wave_ckan_id': '2e0143a5f2a71b8c14d7a4e47ef791bb', 'wave_cohort': 'NTR: Young Netherlands Twin Register', 'wave_cohort_ckan_id': '6f88a94b0bf79a8304ba604c655c08a9', 'wave_description': 'This is the Main Study of the ACTION project (Aggression in Children: Unraveling gene-environment interplay to inform Treatment and interventION strategies Consortium; http://www.action-euproject.eu/). Here, data collection of first-morning urine samples for metabolomics biomarker discovery and buccal-cell DNA samples for (epi)genetics was conducted in a large cohort of young twins. Family members living at the same address as the participating twin pairs were also asked to provide a buccal-cell DNA sample. The twins were selected to be part of a concordant low-scoring twin pair, a concordant high-scoring twin pair, or a discordant twin pair. Aggression had been assessed in the past by the age-appropriate version of the CBCL (Achenbach System of Empirically Based Assessment (ASEBA) Child Behavior Checklist). During the urine and buccal-cell collection, parents of the twins were asked to complete the ASEBA CBCL for school-aged children (6-18 years) to reflect the current child behaviors, and to provide information about health condition of the twins and conditions of urine collection. Biochemical measurement in urine included a dipstick, density (specific gravity), creatinine, neopterin, C-peptide, Substance P, and oxidized DNA/RNA. Metabolomics data of the Main Study together with the samples obtained in the Biochemical Study (ACTIONBB2) were were obtained from three metabolomics platforms: 1) a liquid chromatography mass spectrometry (LC-MS) platform targeting amines; 2) a LC-MS platform targeting steroid hormones; and 3) a gas chromatography (GC) MS platform targeting organic acids. Buccal-cell samples of the twins from the Main Study together with the samples obtained in the Biochemical Study (ACTIONBB2) were used for genome-wide methylation measurement on the Infinium MethylationEPIC BeadChip Kit (after conclussion of the ACTION project additional twin pairs and siblings were also measured on this platform). DNA samples from all family members were genotyped on the Affymetrix Axiom or Illumina GSA genotyping arrays.', 'wave_end_date_collection': '2017-01-01', 'wave_start_date_collection': '2016-01-01', 'wave_subject_codes': ['PC'], 'wave_title': 'YC_ACTIONBB3', 'wave_universe': '72-156'}, {'wave_ckan_id': '8fb82c775194379af04d33ee9bba53db', 'wave_cohort': 'NTR: Young Netherlands Twin Register', 'wave_cohort_ckan_id': '6f88a94b0bf79a8304ba604c655c08a9', 'wave_description': 'This project is the fifth measurement of a longitudinal study into the development of intelligence and problem behaviour (waves one and two not included in CD2) to which additional participants were recruited (twins with siblings and their parents). The test protocol consisted of a physical part and a psychological part. Physical measurements included cardiovascular functioning (assessed with the VU-AMS device), a physical examination with basic anthropometric measurements and the collection of saliva, DNA and fingerprints. The psychological part consisted of a series of cognitive tests that measured the following abilities: intelligence (Wechsler Intelligence Scale for Children, WISC-R or Revised Amsterdamse Kinder Intelligentie Test, RAKIT); inhibition (Stroop); spontaneous production of words (Verbal fluency); verbal learning and memory (California Verbal Learning Task, CVLT); emotion recognition (Reading the mind in the eyes); perceptual speed (Π inspection time task); spatial short term memory (n-back task and Corsi block tapping task). Furthermore, some questionnaires were administered to the participants (Autism-Spectrum Quotient, Tanner self-report), mothers of the twins (Social Responsiveness Scale) and research assistants (Test Observation form).', 'wave_end_date_collection': '2006-01-01', 'wave_start_date_collection': '2004-01-01', 'wave_subject_codes': ['MM'], 'wave_title': 'YE_COG18', 'wave_universe': '216'}, {'wave_ckan_id': '203163b298931a92c85fd3c957f92ee6', 'wave_cohort': 'NTR: Young Netherlands Twin Register', 'wave_cohort_ckan_id': '6f88a94b0bf79a8304ba604c655c08a9', 'wave_description': 'The survey for triplets at age 1 is a 2-page survey that includes items on pregnancy, gestational age, smoking and alcohol consumption during pregnancy, and mode of delivery. The content of this survey is highly comparable with the survey 1 for twins (YS_1).', 'wave_end_date_collection': '2001-01-01', 'wave_start_date_collection': '1990-01-01', 'wave_subject_codes': ['MM'], 'wave_title': 'YS_TRIP1', 'wave_universe': '12'}, {'wave_ckan_id': '913e7214793a3495c2bfd111288b3077', 'wave_cohort': 'NTR: Young Netherlands Twin Register', 'wave_cohort_ckan_id': '6f88a94b0bf79a8304ba604c655c08a9', 'wave_description': 'In 2008, a combination of the triplet surveys at age 1 and 2 was sent to mothers of all triplets. Since 2009, the combined survey 1 and 2 served as the first survey for newly registered triplets. The combined survey comprises items on pregnancy, gestational age, smoking and alcohol consumption during pregnancy, mode of delivery, breastfeeding, attaining miles stones, and growth.', 'wave_start_date_collection': '2008-01-01', 'wave_subject_codes': ['MM'], 'wave_title': 'YS_TRIP1_2', 'wave_universe': '12-24'}] |
| resources | [] |
| tags | [] |
| groups | [] |
| relationships_as_subject | [] |
| relationships_as_object | [] |
| tracking_summary | {'total': 32, 'recent': 3} |
